Organisation of the first Ki-NOA day

Transfer of chiral information for static and dynamic electroanalytical approaches

IECB: salle Haut Brion, 15th of oct. at 11H00

All electrochemical processes are intrinsically “intelligent”; chirality can make them even smarter, endowing them with a superior level of selectivity, and making them applicable to issues of much higher added value, e.g. in the pharmaceutical and biological field, or in smart devices. In spite of this, chiral electrochemistry is still immature.

With respect to former approaches, the inherent chirality concept can provide the breakthrough. [1] In fact, it implies chirality and key functional properties, like electroactivity, to originate from the same structural element, which coincides with the main backbone of the chiral selector. Such unique identity endows the selector with extraordinary chirality manifestations and can be propagated from molecular level to the macroscopic one. Unprecedented recognition, in terms of energy differences, was recently observed, implementing inherently chiral materials both as enantiopure electrode surfaces and media. [2, 3] Recently, attractive potentialities of these systems were also exploited in the field of bipolar electrochemistry [4] and in the one of autonomous swimmers [5] allowing to correlate the output signal with the concentration of the enantiomers present in solution.

 

[1] F. Sannicolò, S. Arnaboldi, T. Benincori, V. Bonometti, R. Cirilli, L. Dunsch, W. Kutner, G. Longhi, P.R. Mussini, M. Panigati, M. Pierini, S. Rizzo, Potential-Driven Chirality Manifestations and Impressive Enantioselectivity by Inherently Chiral Electroactive Organic Films. 2014, ANGEWANDTE CHEMIE INTERNATIONAL EDITION, 53, 2623-2627.

[2] S. Arnaboldi, T. Benincori, R. Cirilli, W. Kutner, M. Magni, P.R. Mussini, K. Noworyta, F. Sannicolò, Inherently chiral electrodes: the tool for chiral voltammetry. 2015, CHEMICAL SCIENCE, 6, 1706-1711.

[3] S. Rizzo, S. Arnaboldi, V. Mihali, R. Cirilli, A. Forni, A. Gennaro, A.A. Isse, M. Pierini, P.R. Mussini, F. Sannicolò, “Inherently Chiral” Ionic-Liquid Media: Effective Chiral Electroanalysis on Achiral Electrodes. 2017, ANGEWANDTE CHEMIE INTERNATIONAL EDITION, 56, 2079-2082.

[4] S. Arnaboldi, B. Gupta, T. Benincori, G. Bonetti, R. Cirilli, A. Kuhn, Absolute Chiral Recognition with Hybrid Wireless Electrochemical Actuators. 2020, ANALYTICAL CHEMISTRY, 10.1021/acs.analchem.0c01817.

[5] S. Arnaboldi; G. Salinas; A. Karajic; P. Garrigue; T. Benincori; R. Cirilli; S. Bichon; S. Gounel; N. Mano; A. Kuhn, Direct dynamic readout of molecular chirality with autonomous enzyme driven swimmers. 2021, NATURE CHEMISTRY, 10.1038/s41557-021-00798-9.

Combination of achiral plasmonic nanoparticles and quantum dots with chiral molecules – plasmonic CD, enhancement of molecular CD, excitonic CD models of interaction of chiral molecule and electronic states of the metal/semiconductor nanoparticles.

The seminars will take place in the auditorium of IECB.