2022-12-15
News: Chiral-imprinted mesoporous Pt-Ir alloy surfaces were combined in a synergetic way with electrochemiluminescence (ECL) to detect the two enantiomers of phenylalanine (PA) as a model compound, acting simultaneously as a chiral target and as a co-reactant to generate significant differences in ECL signals. The chiral features of the metal surfaces are converted into an enantioselective electrogeneration of the excited state of the [Ru(bpy)3]2+ dye, which in fine produces the differentiating light emission with up to 20-fold differences in intensity for the two enantiomers. These findings open up the possibility of developing new ECL-based bioassays and microscopy of chiral environments.
S. Butcha, J. Yu, Z. Pasom, B. Goudeau, C. Wattanakit, N. Sojic, A. Kuhn
ChemComm 58 (2022) 10707-10710
Laboratory : ISM
https://doi.org/10.1039/D2CC02562K
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